Rupert Beale

Rupert Beale is a clinician scientist group leader at the Francis Crick Institute.

On Omicron

Rupert Beale, 16 December 2021

We have seen​ plenty of viral variants, some with Spike genes of sufficient interest to merit a Greek letter. Spike is the virus’s entry weapon, and the bit of the virus that’s targeted by vaccines. If your antibodies block Spike, you block the virus – and if Spike has mutated, it may have become better at dodging those antibodies. Delta has been the most vicious variant so...

From The Blog
13 October 2023

For their work on understanding and using the chemical modifications of RNA to make better vaccines, Katalin Karikó and Drew Weissman have been awarded this year’s Nobel Prize for Physiology or Medicine – the only surprise being that they didn’t get it last year. Your share of the prize has probably been deposited into your deltoid muscle, if at some point you got the Pfizer/BioNTech or Moderna Covid vaccine.

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